NFL Picks, Predictions Against The Point Spread, Week 2 a quarterback who makes good decisions (and is one of the best in the league in. NFL picks against the spread , Week 2: Browns, Bills are I also picked the Bills to cover a 7- point spread on the road against Carolina. tossup for me, so the home team is probably the best bet for such a close spread. NFL Week 3 early odds: Browns favored in a road game for first time in three years. Here's an early look at the lines for all NFL games being played in Week 3 Of course, we should probably point out that this includes a 2 -1 ATS the Eagles went ATS as a home favorite, which was the best mark of.